zurück Home | Rezeptorstatus von Metastasen des Mamma - Karzinoms | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
allgemeines | Bei der Behandlung geht man davon aus, dass Rezidive und Metastasen den gleichen Rezeptorstatus haben, wie der Primärtumor. Im Einzelfall gibt es auch Abweichungen. Literaturzusammenstellung (1) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Östrogen - Rezeptor von Metastasen | Primärtumor Östrogen - Rezeptor positiv
Metastasen / Rezidive Östrogen-Rezeptor positiver Tumoren sind zu 4/5 ebenfalls Rezeptor positiv in 1/5 Rezeptor negativ. |
Primärtumor Östrogen - Rezeptor negativ
Metatasen / Rezidive Östrogen-Rezeptor negativer Tumoren sind zu 4/5 ebenfalls Rezeptor negativ in 1/5 Rezeptor positiv. |
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Progesteron - Rezeptor von Metastasen | Primärtumor Progesteron - Rezeptor positiv
Metastasen / Rezidive Progesteron-Rezeptor positiver Tumoren sind nur zur Häfte Rezeptor positiv in knapp der Hälfte Rezeptor negativ. |
Primärtumor Progesteron - Rezeptor negativ
Metastasen / Rezidive Progesteron-Rezeptor negativer Tumoren sind zu 5/6 auch Rezeptor negativ in 1/6 Rezeptor positiv. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quellen |
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Curtit E, Nerich V, Mansi L et al.: Discordances in estrogen receptor Status, progesterone receptor Status, and HER2 Status between primary breast cancer and metastasis. The Oncologist 18(2013):667-674 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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