| Studie | Therapie | Kontroll-Zeit | IMR | Art |
| NSABP B-06 (1) | 1976–1984 | 39 (5–95) M | 110 von 1108 | 86% gleicher Quadrant |
| Uppsala-Orebro (2) | 1981–1988 | 10a | 57 von 381 | 69% OP-Gebiet, 3,6% OP-Narbe, 3,6% Haut über OP-Gebiet, 23,6% Restbrust |
| Ontario Clinical Oncology Group (3) | 1984–1989 | 43M | 131 von 837 | 86%% OP-Gebiet |
| Milan III (4) | 1987–1989 | 9a | 75 von 579 | 85% OP-Gebiet, 15% Restbrust |
| SweBCG 91-RT (5) | 1991–1997 | 5a | 104 von 1178 | 90% gleicher Quadrant |
Pathologic findings from the National Surgical Adjuvant Breast Project (protocol 6). II. Relation of local breast recurrence to multicentricity.
Cancer. 1986;57:1717–1724.
2.) Liljegren G, Holmberg L, Bergh J, et al.:
10-Year results after sector resection with or without postoperative radiotherapy for stage I breast cancer: a randomized trial.
J Clin Oncol. 1999;17:2326–2333.
3.) Clark RM, Whelan T, Levine M, et al.:
Randomized clinical trial of breast irradiation following lumpectomy and axillary dissection for node-negative breast cancer: an update. Ontario Clinical Oncology Group.
J Natl Cancer Inst. 1996;88:1659–1664.
4.) Veronesi U, Marubini E, Mariani L, et al.:
Radiotherapy after breast-conserving surgery in small breast carcinoma: long-term results of a randomized trial.
Ann Oncol. 2001;12:997–1003.
5.) Malmstrom P, Holmberg L, Anderson H, et al.:
Breast conservation surgery, with and without radiotherapy, in women with lymph node-negative breast cancer: a randomised clinical trial in a population with access to public mammography screening.
Eur J Cancer. 2003;39:1690–1697.
