zurück	intramammäre Rezidive (IMR) nach brusterhaltender Therapie
Studie	Therapie	Kontroll-Zeit	IMR	Art
NSABP B-06	1976–1984	39 (5–95) M	110 von 1108	86% gleicher Quadrant
Uppsala-Orebro	1981–1988	10a	57 von 381	69% OP-Gebiet, 3,6% OP-Narbe, 3,6% Haut über OP-Gebiet, 23,6% Restbrust
Ontario Clinical Oncology Group	1984–1989	43M	131 von 837	86%% OP-Gebiet
Milan III	1987–1989	9a	75 von 579	85% OP-Gebiet, 15% Restbrust
SweBCG 91-RT	1991–1997	5a	104 von 1178	90% gleicher Quadrant
Quellen	Fisher ER, Sass R, Fisher B, Gregorio R, Brown R, Wickerham L. Pathologic findings from the National Surgical Adjuvant Breast Project (protocol 6). II. Relation of local breast recurrence to multicentricity. Cancer. 1986;57:1717–1724. [26]Liljegren G, Holmberg L, Bergh J, et al. 10-Year results after sector resection with or without postoperative radiotherapy for stage I breast cancer: a randomized trial. J Clin Oncol. 1999;17:2326–2333. Clark RM, Whelan T, Levine M, et al. Randomized clinical trial of breast irradiation following lumpectomy and axillary dissection for node-negative breast cancer: an update. Ontario Clinical Oncology Group. J Natl Cancer Inst. 1996;88:1659–1664. Veronesi U, Marubini E, Mariani L, et al. Radiotherapy after breast-conserving surgery in small breast carcinoma: long-term results of a randomized trial. Ann Oncol. 2001;12:997–1003. [28]Malmstrom P, Holmberg L, Anderson H, et al. Breast conservation surgery, with and without radiotherapy, in women with lymph node-negative breast cancer: a randomised clinical trial in a population with access to public mammography screening. Eur J Cancer. 2003;39:1690–1697.

Impressum .....................................................................................Zuletzt geändert am 09.08.2014 17:41