Lungen - Metastasen: Radiofrequenzablation
- Colorectale Tumoren
- Mamma-Ca
- Hepatozelluläres Ca
- Nierenzell-Ca
- Bronchial-Ca
 | erfolgreiche Ablation | ||
| alle | 95/130 (73.1%) | ||
| Metastasengröße | bis 30mm | 90/110 | p<0,0001 |
| über 30mm | 5/20 | ||
| Lage | peripher | 80/100 80% | p<0,002 | zentral | 15/30 50% |
| OS | 12 M | 91,3% | |
| 24 M | 75% | ||
| Mortalität | intra-OP | 0% | |
| 60 Tage | 0% | ||
| Pneumothorax | 8.5% (11 of 130) | ||
| Absaugung erforderlich | 1/11 (0.8%) | ||
| Lungenblutung | 8/130 (6.2%) |
- 68 Colorectale Tumoren
- 12 Melanom
- 11 Nierenzell-Ca
- 26,4% Vollremission
- 37,2% PR
- 21,7% SD
- 14,7% PD
Microwave Ablation Therapy: Clinical Utility in Treatment of Pulmonary Metastases.
Radiology 261(2011):643-51. doi: 10.1148/radiol.11101643.
2.) Lencioni R, et al.:
Response to radiofrequency ablation of pulmonary tumours: A prospective, intention-to-treat, multicentre clinical trial (the rapture study).
Lancet Oncol 9(2008):621–8
3.) Kodama H, et al.:
Lung radiofrequency ablation for the treatment of unresectable recurrent non-small-cell lung cancer after surgical intervention.
Cardiovasc Intervent Radiol 35(2011): 563–9
4.) Schneider T, et al.:
The efficacy of bipolar and multipolar radiofrequency ablation of lung neoplasms—results of an ablate and resect study.
Eur J Cardiothorac Surg 39(2011):968–73
5.) Simon CJ , et al.:
Pulmonary radiofrequency ablation: long-term safety and efficacy in 153 patients.
Radiology 243(2007): 268–75
6.) Hiraki T, et al.:
Percutaneous radiofrequency ablation for pulmonary metastases from colorectal cancer: midterm results in 27 patients.
J Vasc Interv Radiol 18(2007):1264–9
7.) Yamakoado K, et al.:
Radiofrequency ablation for the treatment of unresectable lung metastases in patients with colorectal cancer: a multicenter study in Japan.
J Vasc Interv Radiol 18(2007): 393–8
8.) Choe Y, et al.:
The use of PTC and RFA as treatment alternatives with low procedural morbidity in non-small cell lung cancer.
Eur J Cancer 45(2009): 1773–9
9.) Pennathur A, et al.:
Image-guided radiofrequency ablation of lung neoplasm in 100 consecutive patients by a thoracic surgical service.
Ann Thorac Surg 87(2009): 1030–6
10.) Chua TC, et al.:
Long-term outcome of image-guided percutaneous radiofrequency ablation of lung metastases: an open-labeled prospective trial of 148 patients.
Ann Oncol 21(2010): 2017–22
11.) Hiraki T, Gobara H, Mimura H:
Percutaneous radiofrequency ablation of clinical stage I non-small cell lung cancer.
J Thorac Cardiovasc Surg 142(2011): 24–30
12.) Kashima M, et al.:
Complications after 1000 lung radiofrequency ablation sessions in 420 patients: a single center’s experiences.
Am J Roentgenol 197(2011): W576–80
13.) Huang L, et al.:
Is radiofrequency thermal ablation a safe and effective procedure in the treatment of pulmonary malignancies?
Eur J Cardiothorac Surg 39(2011): 348–51
14.) Bretschneider T, et al.:
Sicherheit und Effektivität der CT-Gesteuerten Radiofrequenzablation (RFA) in der Behandlung von Lungenmalignomen.
RöFo 186(2014) S1: S147