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niedrigmalige NHL: Kurative Radiotherapie früher Stadien

Autor Zielvolumen Patienten % RFS % OS
5a10a15a 5a10a15a
MacManus 1996 (1) IF-EF 136 48 36- 82 58-
TNI 41 77 67 - 85 73-
Stuschke 1997 (2) EF-TCI 117 71 8a: 59 - 89 8a: 89-
Wilder 2001 (3) IF 80 63 57 41 82 65 43
Voss 2001 (4) IF 228 80 61 55 87 62 52
Ott 2003 (5) IF-EF-TNI 58 73 63 - 86 69-
Neumann 2003 (6) IF-EF-TNI 116 62 48 - 76 51-
Petersen 2004 (7) IF 460 56 41 - 79 62-
Guadagnolo 2006 (8) IF-EF 79 72 46 39 93 75 62
Eich 2009 (9) IF-EF-TNI 65 55 37 - 86 55-

Quellen

1.) MacManus, M. P., Hoppe, R.T.:
Is radiotherapy curative for stage I and II low grade follicular lymphoma? Results of a long term follow-up study of patients treated at Stanford University.
JCO 14(1996):1282-1290

2.) Stuschke M, Hoederath A, Sack H et al.:
Extended field and total central lymphatic radiotherapy for early stage lymph node centroblastic-centrocytic lymphomas. Results of a prospective multicenter study.
Cancer 80(1997):2273-84

3.) Wilder RB, Jones D, Tucker SL et al.:
Long-term results with radiotherapy for stage I-II follicular lymphomas.
IJROBP 51(2001):1219-27

4.) Voss NJS, Klasa RJ, Fainey et al.:
The treatment of early stage, low grade non-Hodgkin’s lymphoma with involved field irradiation. The BCCA experience.
Ann Hematol. 80(2001) Suppl III:B153 (Abstract)

5.) Ott OJ, Rodel C, Gramatzki M et al.:
Radiotherapy for stage I-III nodal low-grade non-Hodgkin's lymphoma.
Strahlenther Onkol. 179(2003):694-701

6.) Neumann H, Blanck H, Koch R et al.:
Follicle centre lymphoma: treatment results for stage I and II.
Strahlenther Onkol. 179(2003):840-46

7.) Petersen PM, Gospodarowicz MK, Tsang R et al.:
Longterm outcome in stage I and II follicular lymphoma following treatment with Involved Field radiation therapy alone.
JCO 22(2004):6521

8.) Guadagnolo BA, Li S, Neuberg D et al.
Long-term outcome and mortality trends in early-stage, Grade 1-2 follicular lymphoma treated with radiation therapy.
IJROBP 64(2006):928-34

9.) Eich HT, Heimann M, Stutzer H, et al.
Long-term outcome and prognostic factors in early-stage nodal low-grade non-hodgkin's lymphomas treated with radiation therapy.
Strahlenther Onkol. 185(2009):288-95

10.) Engelhard M:
Strahlentherapie der indolenten NHL in Frühstadien. Interimanalyse einer prospektiven Therapiestudie.
Symposium „Klinische Onkologie“ Düsseldorf 2011/2012

Impressum .....................................................................................Zuletzt geändert am 21.09.2012 16:22