niedrigmalige NHL: Kurative Radiotherapie früher Stadien |
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Autor | Zielvolumen | Patienten | % RFS | % OS | ||||
5a | 10a | 15a | 5a | 10a | 15a | |||
MacManus 1996 (1) | IF-EF | 136 | 48 | 36 | - | 82 | 58 | - |
TNI | 41 | 77 | 67 | - | 85 | 73 | - | |
Stuschke 1997 (2) | EF-TCI | 117 | 71 | 8a: 59 | - | 89 | 8a: 89 | - |
Wilder 2001 (3) | IF | 80 | 63 | 57 | 41 | 82 | 65 | 43 |
Voss 2001 (4) | IF | 228 | 80 | 61 | 55 | 87 | 62 | 52 |
Ott 2003 (5) | IF-EF-TNI | 58 | 73 | 63 | - | 86 | 69 | - |
Neumann 2003 (6) | IF-EF-TNI | 116 | 62 | 48 | - | 76 | 51 | - |
Petersen 2004 (7) | IF | 460 | 56 | 41 | - | 79 | 62 | - |
Guadagnolo 2006 (8) | IF-EF | 79 | 72 | 46 | 39 | 93 | 75 | 62 |
Eich 2009 (9) | IF-EF-TNI | 65 | 55 | 37 | - | 86 | 55 | - |
Quellen |
1.) MacManus, M. P., Hoppe, R.T.: Is radiotherapy curative for stage I and II low grade follicular lymphoma? Results of a long term follow-up study of patients treated at Stanford University. JCO 14(1996):1282-1290 2.) Stuschke M, Hoederath A, Sack H et al.: Extended field and total central lymphatic radiotherapy for early stage lymph node centroblastic-centrocytic lymphomas. Results of a prospective multicenter study. Cancer 80(1997):2273-84 3.) Wilder RB, Jones D, Tucker SL et al.: Long-term results with radiotherapy for stage I-II follicular lymphomas. IJROBP 51(2001):1219-27 4.) Voss NJS, Klasa RJ, Fainey et al.: The treatment of early stage, low grade non-Hodgkin’s lymphoma with involved field irradiation. The BCCA experience. Ann Hematol. 80(2001) Suppl III:B153 (Abstract) 5.) Ott OJ, Rodel C, Gramatzki M et al.: Radiotherapy for stage I-III nodal low-grade non-Hodgkin's lymphoma. Strahlenther Onkol. 179(2003):694-701 6.) Neumann H, Blanck H, Koch R et al.: Follicle centre lymphoma: treatment results for stage I and II. Strahlenther Onkol. 179(2003):840-46 7.) Petersen PM, Gospodarowicz MK, Tsang R et al.: Longterm outcome in stage I and II follicular lymphoma following treatment with Involved Field radiation therapy alone. JCO 22(2004):6521 8.) Guadagnolo BA, Li S, Neuberg D et al. Long-term outcome and mortality trends in early-stage, Grade 1-2 follicular lymphoma treated with radiation therapy. IJROBP 64(2006):928-34 9.) Eich HT, Heimann M, Stutzer H, et al. Long-term outcome and prognostic factors in early-stage nodal low-grade non-hodgkin's lymphomas treated with radiation therapy. Strahlenther Onkol. 185(2009):288-95 10.) Engelhard M: Strahlentherapie der indolenten NHL in Frühstadien. Interimanalyse einer prospektiven Therapiestudie. Symposium „Klinische Onkologie“ Düsseldorf 2011/2012 | |||||||
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Impressum .....................................................................................Zuletzt geändert am 21.09.2012 16:22