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EORTC-Studien: Sarkom und Knochen-Tumoren

Allgemeines EORTC Soft Tissue and Bone Sarcoma Group
1202 Randomized phase II trial of cabazitaxel or prolonged infusional ifosfamide in metastatic or inoperable locally advanced dedifferentiated liposarcoma
62092 A phase III randomized study of preoperative radiotherapy plus surgery versus surgery alone for patients with Retroperitoneal sarcomas (RPS) - STRASS
62091 TRUSTS : A phase IIb/III multicenter study comparing the efficacy of Trabectedin administered as a 3-hour or 24 hour infusion to doxorubicin in patients with advanced or metastatic untreated soft tissue sarcoma
62063 A phase III randomized study evaluating surgery of residual disease in patients with metastatic gastro-intestinal stromal tumor responding to Imatinib mesylate.
62072 A randomized double blind phase III trial of Pazopanib versus placebo in patients with soft tissue sarcoma whose disease has progressed during or following prior therapy.
62052 Phase II study of E7389 administered as an IV infusion on day 1 and 8 every 3 weeks in pretreated patients with advanced and/or metastatic soft tissue sarcoma
62061 Randomized phase II study of brostallicin (PNU-166196A) versus doxorubicin as first line chemotherapy in patients with advanced or metastatic soft tissue sarcoma
62043 Phase II study of GW786034 in patients with relapsed or refractory soft tissue sarcoma
62024 Intermediate and high risk localized,completely resected, gastrointestinal stromal tumors (GIST) expressing KIT receptor : a controlled randomized trial on adjuvant Imatinib mesylate (Glivec) versus no further therapy after complete surgery.
62027 Phase 2 study of Glivec (Imatinib) in locally advanced and/or metastatic soft tissue sarcomas expressing the t(17;22) (q22;q13) translocation resulting in a COL1A1/PDGF- beta fusion protein i.e. DermatoFibroSarcoma Protuberans (DFSP) and Giant Cell Fibroblastoma (GCF)
62012 Randomised trial of single agent doxorubicin versus doxorubicin plus ifosfamide in the first line treatment of advanced or metastatic soft tissue sarcoma
62022 Phase 2 study of Iressa (ZD 1839) in locally advanced and/or metastatic synovial sarcoma expressing HER1/EGFRI.
62006 Exatecan as second line treatment in advanced adult soft tissue sarcoma: A phase II study of the EORTC Soft Tissue and Bone sarcoma Group. (Study only open for patients with Leiomyosarcoma)
62011 Efficacy and safety study of Brostallicin in patients with locally advanced or metastatic soft tissue sarcoma failing one prior chemotherapy treatment
62991 Phase II pilot study of moderate dose radiotherapy for inoperable aggressive fibromatosis
62002 Phase I study to determine the safety of Caelyx (Doxorubicin HCI, pegylated liposomal) in combination with Ifosfamide in previously untreated adult patients with advanced and/or metastatic soft tissues sarcomas.
62981 EURO-EWING 99 EUROpean Ewing tumour Working Initiative of National Groups Ewing Tumour Studies 1999
62005 Phase III randomised, intergroup, international trial assessing the clinical activity of STI-571 at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumours (GIST) expressing the KIT receptor tyrosine kinase (CD117)
62993 A phase II study to evaluate the role of weekly Cisplatin with oral Etoposide in Ewing's sarcoma and primitive neuroectodermal tumour (PNET) with metastasis outside the lung and the pleura.
62001 Dose finding and phase II study of STI 571 in advanced soft tissue sarcoma.
62982 Phase II study on ET-743 in advanced soft tissue sarcomas of the adult.
62972 Phase II Study on Gemcitabine in advanced soft tissue sarcomas of the adult
62971 Randomized phase III trial of two investigational schedules of Ifosfamide versus standard dose Doxorubicin in patients with advanced or metastatic soft tissue sarcoma.
62951 Phase II study on Tomudex in advanced soft tissue sacromas of the adult
62961 Randomized study comparing neoadjuvant chemotherapy Etoposide + Ifosfamide + Adriamycin (EIA) combined with regional hyperthermia (RHT) Vs neoadjuvant chemotherapy alone in the treatment of high-risk soft tissue sarcomas in adults. An Intergroup study with the European Society for hyperthermic oncology.
62962 Phase II Study of Caelyx (Doxorubicin HCl, pegylated liposomal) or Doxorubicin in previously untreated adult patients with advanced and/or metastatic soft tissue sarcomas.
62953 Phase II study on HD Ifosfamide in advanced soft tissue sarcomas of the adult
62922 Phase II trial of temozolomide in adult patients with advanced soft tissue sarcoma
62933 Metastasectomy and chemotherapy for lung metastases from soft tissue sarcoma. A randomized phase III study (an Intergroup Study with the Scandinavian Sarcoma Group)
62941 Randomized multicenter phase III trial comparing Docetaxel to Doxorubicin in previously untreated patients with advanced and/or metastatic soft tissue sarcoma
62931 Randomized phase III trial of adjuvant chemotherapy with high-dose doxorubicin, ifosfamide and lenograstim in high grade soft tissue sarcoma.
62932 Phase II study of daily oral vepeside (etoposide VP16-213) as second line treatment in advanced soft tissue sarcomas
80931 EORTC/MRC/SIOP/UKCCSG/CSG collaborative phase III randomized trial of chemotherapy with or without granulocyte colony-stimulating factor in operable osteosarcoma
62921 A phase II trial with taxotere (RP56976) in advanced soft tissue sarcomas of the adult
62903 Randomized phase III study comparing conventional dose Doxorubicin plus Ifosfamide vs high dose Doxorubicin plus Ifosfamide plus granulocyte-macrophage colony stimulating factor (GM-CSF) in the treatment of advanced soft tissue sarcomas in adults
62912 Randomized phase II study comparing two different Ifosfamide dose regimens
62911 Phase II study of liposomal muramyl tripeptide phosphatidylethanolamine (MTP/PE) in advanced soft tissue sarcoma of the adult
62901 Randomized phase II-III study comparing adriamycin versus two schedules of high dose Epirubicin in advanced soft tissue sarcoma
62902 PHASE II STUDY OF DAILY ORAL MILTEFOSINE (HEXADECYLPHOSPHOCHOLINE) IN ADVANCED SOFT TISSUE SARCOMAS OF THE ADULT.
62883 Phase II clinical study of the use of granulocyte-macrophage colony-stimulating factor (GM-CSF) with chemotherapy (adriamycin andifosfamide) in the treatment of advanced soft tissue sarcomas in adults
62882 PHASE II TRIAL OF FOTEMUSTINE IN PATIENTS WITH ADVANCED SOFT TISSUE SARCOMA
62881 PHASE II STUDY OF ACNU IN METASTATIC SOFT TISSUE SARCOMA
62874 Randomized phase II study of neoadjuvant chemotherapy in soft tissue sarcomas in adults
62871 Phase II Chemotherapy with m-Azidopyrimethamine in Adults with Metastatic Soft Tissue Sarcoma (Summary Last Modified 05/88)
62863 Phase II study of Mitozolomide in metastatic soft tissue sarcoma
62862 Phase II study of Iproplatin in advanced Osteogenic Sarcoma
62861 Phase II Chemotherapy with Methylene Dimethane Sulphonate in Patients with Soft Tissue Sarcomas
62851 Phase III trial of first line chemotherapy (adriamycin vs adriamycin + ifosfamide vs cyvadic) in advanced soft tissue sarcoma
62832 Phase II study of Ifosfamide in advanced osteosarcoma
62771 Randomized trial for Adjuvant Chemotherapy in soft tissue sarcoma
1317 Phase II study of cabozantinib in patients with gastrointestinal stromal tumor (GIST) who progressed during neoadjuvant, adjuvant or palliative therapy with imatinib and sunitinib
62831 Phase II clinical study of VP16-213 (etoposide) in advanced soft tissue sarcoma in adults
62793 Phase II study of PALA in soft tissue sarcoma
62792 Phase II trial of low dose methotrexate in soft tissue sarcoma
62761 Phase III trial comparing two schedules of cyvadic in metastatic soft tissue sarcoma
62782 Phase II trial of high dose versus low dose methotrexate in advanced osteosarcoma
62794 Phase II trial of cisplatin in advanced osteosarcoma
62801 Phase II-III trial of adriamycin versus 4'epiadriamycin in advanced soft tissue sarcoma
62802 Phase II trial of adriamycin versus carminomycin in advanced soft tissue sarcoma
62803 Phase II trial of 9-hydroxy-2N-methyl-ellipticinium (9HME) in advanced soft tissue sarcoma in adults
62841 Phase II trial of high dose DTIC in advanced soft tissue sarcomas of the adult
62842 Phase II clinical trial of ifosfamide + adriamycin in advanced soft tissue sarcoma in adults
62843 Phase II clinical study of TGU in advanced soft tissue sarcoma in adults (quick procedure)
62812 Phase II clinical trial of mitomycin C in advanced soft tissue sarcomas in adults
62821 Randomized phase II study of cyclophosphamide versus ifosfamide in advanced soft tissue sarcoma
62873 Phase II study of the combination doxorubicin/ifosfamide/DTIC in advanced soft tissue sarcomas of the adult
62113 A randomized double-blind phase II study evaluating the role of maintenance therapy with cabozantinib in High Grade Undifferentiated Uterine Sarcoma (HGUS) after stabilization or response to doxorubicin +/- ifosfamide following surgery or in metastatic first line treatment
55116 A Phase III Randomized Trial of Gemcitabine plus Docetaxel followed by Doxorubicin v. observation for uterus-limited, High Grade Uterine Leiomyosarcoma
1225 Phase II study of anti-IGF-1R/IR (A7487/OSI-906) in patients with relapsed and/or refractory Ewing Sarcoma

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