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Nieren - Karzinom: Prognose

UICC-Stadium

blauer Punkt Stadium 5a-Überleben
blauer Punkt I 95%
blauer Punkt II 89%
blauer Punkt III 60%
blauer Punkt IV 25%
mRCC metastasiertes Nierenzellkarzinom
blauer Punkt Motzer - Hudes - Kriterien
blauer Punkt
  • Intervall < 1 Jahr
  • Metastasen in mehreren Organen
  • KI < 80
  • Anämie
  • LDH > 1,5 x Normalwert
  • Serum-ca > 10mg/dl
max 1 Kriterium: Survival 2 Jahre - low risk
> 2 Kriterien: Survival 4 - 8 Monate - high risk
Quellen Motzer RJ, Mazumdar M, Bacik J, et al:
Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma.
J Clin Oncol 17 (1999):2530-2540

Motzer RJ, Bacik J, Murphy BA, et al:
Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma.
J Clin Oncol 20(2002):289-296

Mekhail TM, Abou-Jawde RM, Boumerhi G, et al.
Validation and extension of the Memorial Sloan-Kettering prognostic factors model for survival in patients with previously untreated metastatic renal cell carcinoma.
J Clin Oncol 23 (2005):832-41.

Impressum .....................................................................................Zuletzt geändert am 22.09.2012 15:31