zurück	18F-Choline PET/CT
allgemeines	Wird zur Metastasensuche und zum Restaging eingesetzt.
abnorme Anreicherung	15 Fälle = 18.7% 12 Entzündung 1 low grade -Lymphom 1 Meningiom 1 low-grade Hirntumor
physiologische Aufnahme	Leber, Pankreas, Milz, Speicheldrüsen, Tränendrüsen, Harnwege (Ausscheidung).
Patienten	80 Männer mit primärem Prostata-ca oder PSA-Rezidiv .
Quelle	Schillaci O, Calabria F, Tavolozza M, Cicciò C, Carlani M, Caracciolo CR, Danieli R, Orlacchio A, Simonetti G: 18F-choline PET/CT physiological distribution and pitfalls in image interpretation: experience in 80 patients with prostate cancer. Nucl Med Commun. 31 (2010): 39-45 Universität Rom
	We found abnormal and unexpected PET findings in 15 patients (18.7%), not owing to PC localizations. The majority of these findings were owing to inflammation (12 of 15); a case of low grade lymphoma was detected; two patients showed focal brain uptake of 18F-choline and were subsequently submitted to magnetic resonance: in one a meningioma and in the other a low-grade brain tumour were diagnosed. CONCLUSION: Accurate knowledge of the biodistribution of 18F-choline is essential for the correct interpretation of PET/CT imaging. CT enables differentiation of physiological bowel activity and 18F-choline excretion in the ureters. In our series, 18F-choline uptake in benign pathological conditions mainly included sites of inflammation; nevertheless, accumulation in tumour deposits not because PC cannot be excluded, particularly in the brain, where correlative imaging with magnetic resonance is of the utmost importance.

Impressum ..................................................................................... Zuletzt geändert am 22.09.2012 17:14