zurück Home G-Protein: Class A, Rhodopsin-like
allgemeines
  • Class A, Rhodopsin-like
  • Class B, Secretin receptor family
  • Class C, Metabotropic glutamate/pheromone
  • Class D, Fungal mating pheromone receptors
  • Class E, Cyclic AMP receptors
  • Class F, Frizzled/Smoothened
Subfamilies
  • A1: Chemokine receptor
  • A2: Chemokine receptor, CXC chemokine receptors, Interleukin-8, Adrenomedullin receptor, Duffy blood group, GPCR estrogen receptor
  • A3: Angiotensin II receptor, Apelin receptor, Bradykinin receptor
  • A4: Opioid receptor, Nociceptin receptor, Somatostatin receptor 1, GPCR neuropeptide receptor,
  • A5: Galanin receptor, Cysteinyl leukotriene receptor, Leukotriene B4 receptor, Relaxin receptor, KiSS1-derived peptide receptor, Melanin-concentrating hormone receptor 1, Urotensin-II receptor
  • A6: Cholecystokinin receptor, Neuropeptide FF receptor, Orexin receptor, Vasopressin receptor, GNRHR, Pyroglutamylated RFamide peptide receptor
  • A7: Bombesin receptor, Neuromedin B receptor, Gastrin-releasing peptide receptor, Endothelin receptor, Neuromedin U receptor, Neurotensin receptor, TRHR, Growth hormone secretagogue receptor, Motilin receptor
  • A8: Anaphylatoxin receptors, Chemokine-like receptor 1, Formyl peptide receptor, MAS1 oncogene
  • A9: Melatonin receptor, Neurokinin receptor, Tachykinin receptor, Neuropeptide Y receptor, PRLHR, Prokineticin receptor
  • A10: Glycoprotein hormone receptor, FSHR, Luteinizing hormone/choriogonadotropin receptor, TSHR, Leucine-rich repeat-containing G protein-coupled receptor
  • A11: GPR40-related receptor, Free fatty acid receptor 1, P2 purinoceptor, Purinergic receptor, Hydroxycarboxylic acid receptor 1, Oxoglutarate (alpha-ketoglutarate) receptor 1, Succinate receptor 1
  • A12: P2 purinoceptor, Purinergic receptor, UDP-glucose receptor, Platelet-activating factor receptor
  • A13: Cannabinoid receptor, Lysophosphatidic acid receptor, Sphingosine 1-phosphate receptor, Melanocortin/ACTH receptor, Melanocortin receptor, ACTH receptor
  • A14: Eicosanoid receptor, Prostaglandin receptor, Thromboxane A2 receptor
  • A15: Lysophosphatidic acid receptor, P2 purinoceptor, Protease-activated receptor, Coagulation factor II (thrombin) receptor-like, Epstein-Barr virus induced gene 2
  • A16: Opsins, Rhodopsin, Retinal G protein coupled receptor, Retinal pigment epithelium-derived rhodopsin homolog
  • A17: 5-Hydroxytryptamine (5-HT) receptor, Adrenergic receptor, Dopamine receptor, Trace amine receptor, Histamine H2 receptor
  • A18: Histamine receptor, Adenosine receptor, Muscarinic acetylcholine receptor
  • A19: 5-Hydroxytryptamine (5-HT) receptor Unclassified: Olfactory receptor, Vomeronasal receptor
Subfamily A1 Chemokine receptor IPR000355 Chemokine (C-C motif) receptor 1 (CCR1, CKR1) Chemokine (C-C motif) receptor 2 (CCR2, CKR2) Chemokine (C-C motif) receptor 3 (CCR3, CKR3) Chemokine (C-C motif) receptor 4 (CCR4, CKR4) Chemokine (C-C motif) receptor 5 (CCR5, CKR5) Chemokine (C-C motif) receptor 8 (CCR8, CKR8) Chemokine (C-C motif) receptor-like 2 (CCRL2, CKRX) chemokine (C motif) receptor 1 (XCR1, CXC1) IPR005393 chemokine (C-X3-C motif) receptor 1 (CX3CR1, C3X1) IPR005387 GPR137B (GPR137B, TM7SF1)
Subfamily A2 Chemokine receptor IPR000355 Chemokine (C-C motif) receptor-like 1 (CCRL1 CCRL1, CCR11) Chemokine (C-C motif) receptor 6 (CCR6, CKR6) Chemokine (C-C motif) receptor 7 (CCR7, CKR7) Chemokine (C-C motif) receptor 9 (CCR9, CKR9) Chemokine (C-C motif) receptor 10 (CCR10, CKRA) CXC chemokine receptors IPR001053 Chemokine (C-X-C motif) receptor 3 (CXCR3) Chemokine (C-X-C motif) receptor 4 (CXCR4, Fusin) Chemokine (C-X-C motif) receptor 5 (CXCR5) Chemokine (C-X-C motif) receptor 6 (CXCR6, BONZO) Chemokine (C-X-C motif) receptor 7 (CXCR7, RDC1) IPR001416 Interleukin-8 IPR000174 (IL8R) IL8R-α (IL8RA, CXCR1) IL8R-β (IL8RB, CXCR2) Adrenomedullin receptor (GPR182) Duffy blood group, chemokine receptor (DARC, DUFF) G Protein-coupled Receptor 30 (GPER, CML2, GPCR estrogen receptor)
Subfamily A3 Angiotensin II receptor IPR000248 Angiotensin II receptor, type 1 (AGTR1, AG2S) Angiotensin II receptor, type 2 (AGTR2, AG22) Apelin receptor (AGTRL1, APJ) IPR003904 Bradykinin receptor IPR000496 Bradykinin receptor B1 (BDKRB1, BRB1) Bradykinin receptor B2 (BDKRB2, BRB2) GPR15 (GPR15, GPRF) GPR25 (GPR25)
Subfamily A4 Opioid receptor IPR001418 delta Opioid receptor (OPRD1, OPRD) kappa Opioid receptor (OPRK1, OPRK) mu Opioid receptor (OPRM1, OPRM) Nociceptin receptor (OPRL1, OPRX) Somatostatin receptor IPR000586 Somatostatin receptor 1 (SSTR1, SSR1) Somatostatin receptor 2 (SSTR2, SSR2) Somatostatin receptor 3 (SSTR3, SSR3) Somatostatin receptor 4 (SSTR4, SSR4) Somatostatin receptor 5 (SSTR5, SSR5) GPCR neuropeptide receptor IPR009150 Neuropeptides B/W receptor 1 (NPBWR1, GPR7) Neuropeptides B/W receptor 2 (NPBWR2, GPR8) GPR1 orphan receptor (GPR1) IPR002275
Subfamily A5 Galanin receptor IPR000405 Galanin receptor 1 (GALR1, GALR) Galanin receptor 2 (GALR2, GALS) Galanin receptor 3 (GALR3, GALT) Cysteinyl leukotriene receptor IPR004071 Cysteinyl leukotriene receptor 1 (CYSLTR1) Cysteinyl leukotriene receptor 2 (CYSLTR2) Leukotriene B4 receptor IPR003981 Leukotriene B4 receptor (LTB4R, P2Y7) Leukotriene B4 receptor 2 (LTB4R2) Relaxin receptor IPR008112 Relaxin/insulin-like family peptide receptor 1 (RXFP1, LGR7) Relaxin/insulin-like family peptide receptor 2 (RXFP2, GPR106) Relaxin/insulin-like family peptide receptor 3 (RXFP3, SALPR) Relaxin/insulin-like family peptide receptor 4 (RXFP4, GPR100/GPR142) KiSS1-derived peptide receptor (GPR54) (KISS1R) IPR008103 Melanin-concentrating hormone receptor 1 (MCHR1, GPRO) IPR008361 Urotensin-II receptor (UTS2R, UR2R) IPR000670
Subfamily A6 Cholecystokinin receptor IPR009126 Cholecystokinin A receptor (CCKAR, CCKR) Cholecystokinin B receptor (CCKBR, GASR) Neuropeptide FF receptor IPR005395 Neuropeptide FF receptor 1 (NPFFR1, FF1R) Neuropeptide FF receptor 2 (NPFFR2, FF2R) Orexin receptor IPR000204 Hypocretin (orexin) receptor 1 (HCRTR1, OX1R) Hypocretin (orexin) receptor 2 (HCRTR2, OX2R) Vasopressin receptor IPR001817 Arginine vasopressin receptor 1A (AVPR1A, V1AR) Arginine vasopressin receptor 1B (AVPR1B, V1BR) Arginine vasopressin receptor 2 (AVPR2, V2R) Gonadotrophin releasing hormone receptor (GNRHR, GRHR) IPR001658 Pyroglutamylated RFamide peptide receptor (QRFPR, GPR103) GPR22 (GPR22, GPRM) GPR176 (GPR176, GPR)
Subfamily A7 Bombesin receptor IPR001556 Bombesin-like receptor 3 (BRS3) Neuromedin B receptor (NMBR) Gastrin-releasing peptide receptor (GRPR) Endothelin receptor IPR000499 Endothelin receptor type A (EDNRA, ET1R) Endothelin receptor type B (EDNRB, ETBR) GPR37 (GPR37, ETBR-LP2) IPR003909 Neuromedin U receptor IPR005390 Neuromedin U receptor 1 (NMUR1) Neuromedin U receptor 2 (NMUR2) Neurotensin receptor IPR003984 Neurotensin receptor 1 (NTSR1, NTR1) Neurotensin receptor 2 (NTSR2, NTR2) Thyrotropin-releasing hormone receptor (TRHR, TRFR) IPR009144 Growth hormone secretagogue receptor (GHSR) IPR003905 GPR39 (GPR39) Motilin receptor (MLNR, GPR38)
Subfamily A8 Anaphylatoxin receptors IPR002234 C3a receptor (C3AR1, C3AR) C5a receptor (C5AR1, C5AR) Chemokine-like receptor 1 (CMKLR1, CML1) IPR002258 Formyl peptide receptor IPR000826 Formyl peptide receptor 1 (FPR1, FMLR) Formyl peptide receptor-like 1 (FPRL1, FML2) Formyl peptide receptor-like 2 (FPRL2, FML1) MAS1 oncogene IPR000820 MAS1 (MAS1, MAS) MAS1L (MAS1L, MRG) GPR1 (GPR1) GPR32 (GPR32, GPRW) GPR44 (GPR44) GPR77 (GPR77, C5L2)
Subfamily A9 Melatonin receptor IPR000025 Melatonin receptor 1A (MTNR1A, ML1A) Melatonin receptor 1B (MTNR1B, ML1B) Neurokinin receptor IPR001681 Tachykinin receptor 1 (TACR1, NK1R) Tachykinin receptor 2 (TACR2, NK2R) Tachykinin receptor 3 (TACR3, NK3R) Neuropeptide Y receptor IPR000611 Neuropeptide Y receptor Y1 (NPY1R, NY1R) Neuropeptide Y receptor Y2 (NPY2R, NY2R) Pancreatic polypeptide receptor 1 (PPYR1, NY4R) Neuropeptide Y receptor Y5 (NPY5R, NY5R) Prolactin-releasing peptide receptor (PRLHR, GPRA) IPR001402 Prokineticin receptor 1 (PROKR1, GPR73) Prokineticin receptor 2 (PROKR2, PKR2) GPR19 (GPR19, GPRJ) GPR50 (GPR50, ML1X) GPR75 (GPR75) GPR83 (GPR83, GPR72)
Subfamily A10 Glycoprotein hormone receptor IPR002131 FSH-receptor (FSHR) Luteinizing hormone/choriogonadotropin receptor (LHCGR, LSHR) Thyrotropin receptor (TSHR) Leucine-rich repeat-containing G protein-coupled receptor 4 (LGR4, GPR48) Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5, GPR49) Leucine-rich repeat-containing G protein-coupled receptor 6 (LGR6)
Subfamily A11 GPR40-related receptor IPR013312 Free fatty acid receptor 1 (FFAR1, GPR40) Free fatty acid receptor 2 (FFAR2, GPR43) Free fatty acid receptor 3 (FFAR3, GPR41) GPR42 (GPR42, FFAR1L) P2 purinoceptor IPR002286 Purinergic receptor P2Y1 (P2RY1) Purinergic receptor P2Y2 (P2RY2) Purinergic receptor P2Y4 (P2RY4) Purinergic receptor P2Y6 (P2RY6) Purinergic receptor P2Y8 (P2RY8) Purinergic receptor P2Y11 (P2RY11) Hydroxycarboxylic acid receptor 1 (HCAR1, GPR81) Hydroxycarboxylic acid receptor 2, Niacin receptor 1 (HCAR2, GPR109A) Hydroxycarboxylic acid receptor 3, Niacin receptor 2 (HCAR3, GPR109B, HM74) GPR31 (GPR31, GPRV) GPR82 (GPR82) Oxoglutarate (alpha-ketoglutarate) receptor 1 (OXGR1, GPR80) Succinate receptor 1 (SUCNR1, GPR91)
Subfamily A12 P2 purinoceptor IPR002286 Purinergic receptor P2Y12 (P2RY12) Purinergic receptor P2Y13 (P2RY13, GPR86) IPR008109 Purinergic receptor P2Y14 (P2RY14, UDP-glucose receptor, KI01) IPR005466 GPR34 (GPR34) GPR87 (GPR87) GPR171 (GPR171, H963) Platelet-activating factor receptor (PTAFR, PAFR) IPR002282
Subfamily A13 Cannabinoid receptor IPR002230 Cannabinoid receptor 1 (brain) (CNR1, CB1R) Cannabinoid receptor 2 (macrophage) (CNR2, CB2R) Lysophosphatidic acid receptor IPR004065 Lysophosphatidic acid receptor 1 (LPAR1) Lysophosphatidic acid receptor 2 (LPAR2) Lysophosphatidic acid receptor 3 (LPAR3) Sphingosine 1-phosphate receptor IPR004061 Sphingosine 1-phosphate receptor 1 (S1PR1) Sphingosine 1-phosphate receptor 2 (S1PR2) Sphingosine 1-phosphate receptor 3 (S1PR3) Sphingosine 1-phosphate receptor 4 (S1PR4) Sphingosine 1-phosphate receptor 5 (S1PR5) Melanocortin/ACTH receptor IPR001671 Melanocortin 1 receptor (MC1R, MSHR) Melanocortin 3 receptor (MC3R) Melanocortin 4 receptor (MC4R) Melanocortin 5 receptor (MC5R) ACTH receptor (MC2R), ACTR) GPR3 (GPR3) GPR6 (GPR6) GPR12 (GPR12, GPRC)
Subfamily A14 Eicosanoid receptor IPR008365 Prostaglandin D2 receptor (PTGDR, PD2R) Prostaglandin E1 receptor (PTGER1, PE21) Prostaglandin E2 receptor (PTGER2, PE22) Prostaglandin E3 receptor (PTGER3, PE23) Prostaglandin E4 receptor (PTGER4, PE24) Prostaglandin F receptor (PTGFR, PF2R) Prostaglandin I2 (prostacyclin) receptor (PTGIR, PI2R) Thromboxane A2 receptor (TBXA2R, TA2R)
Subfamily A15 Lysophosphatidic acid receptor IPR004065 Lysophosphatidic acid receptor 4 (LPAR4) Lysophosphatidic acid receptor 5 (LPAR5) Lysophosphatidic acid receptor 6 (LPAR6) IPR002188 P2 purinoceptor IPR002286 Purinergic receptor P2Y10 (P2RY10, P2Y10) Protease-activated receptor IPR003912 Coagulation factor II (thrombin) receptor-like 1 (F2RL1, PAR2) Coagulation factor II (thrombin) receptor-like 2 (F2RL2, PAR3) Coagulation factor II (thrombin) receptor-like 3 (F2RL3, PAR4) Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor) (GPR183) Proton-sensing G protein-coupled receptors GPR4 (GPR4) IPR002276 GPR65 (GPR65) IPR005464 GPR68 (GPR68) IPR005389 GPR132 (GPR132, G2A) IPR005388 GPR17 (GPR17, GPRH) GPR18 (GPR18, GPRI) GPR20 (GPR20, GPRK) GPR35 (GPR35) GPR55 (GPR55) Coagulation factor II receptor (F2R, THRR)
Subfamily A16 Opsins IPR001760[8] Rhodopsin (RHO, OPSD) Opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) (OPN1SW, OPSB) (blue-sensitive opsin) Opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan) (OPN1MW, OPSG) (green-sensitive opsin) Opsin 1 (cone pigments), long-wave-sensitive (color blindness, protan) (OPN1LW, OPSR) (red-sensitive opsin) Opsin 3, Panopsin (OPN3) Opsin 4, Melanopsin (OPN4) Opsin 5 (OPN5, GPR136) Retinal G protein coupled receptor (RGR) Retinal pigment epithelium-derived rhodopsin homolog (RRH, OPSX) (visual pigment-like receptor opsin) IPR001793
Subfamily A17 5-Hydroxytryptamine (5-HT) receptor IPR002231 5-HT2A (HTR2A, 5H2A) 5-HT2B (HTR2B, 5H2B) 5-HT2C (HTR2C, 5H2C) 5-HT6 (HTR6, 5H6) IPR002232 Adrenergic receptor IPR002233 Alpha1A (ADRA1A, A1AA) Alpha1B (ADRA1B, A1AB) Alpha1D (ADRA1D, A1AD) Alpha2A (ADRA2A, A2AA) Alpha2B (ADRA2B, A2AB) Alpha2C (ADRA2C, A2AC) Beta1 (ADRB1, B1AR) Beta2 (ADRB2, B2AR) Beta3 (ADRB3, B3AR) Dopamine receptor IPR000929 D1 (DRD1, DADR) D2 (DRD2, D2DR) D3 (DRD3, D3DR) D4 (DRD4, D4DR) D5 (DRD5, DBDR) Trace amine receptor IPR009132 TAAR1 (TAAR1, TAR1) TAAR2 (TAAR2, GPR58) TAAR3 (TAAR3, GPR57) TAAR5 (TAAR5, PNR) TAAR6 (TAAR6, TAR4) TAAR8 (TAAR8, GPR102) TAAR9 (TAAR9, TAR3) Histamine H2 receptor (HRH2, HH2R) IPR000503
Subfamily A18 Histamine H1 receptor (HRH1, HH1R) IPR000921 Histamine H3 receptor (HRH3) IPR003980 Histamine H4 receptor (HRH4) IPR008102 Adenosine receptor IPR001634 A1 (ADORA1, AA1R) A2a (ADORA2A, AA2A) A2b (ADORA2B, AA2B) A3 (ADORA3, AA3R) Muscarinic acetylcholine receptor IPR000995 M1 (CHRM1, ACM1) M2 (CHRM2, ACM2) M3 (CHRM3, ACM3) M4 (CHRM4, ACM4) M5 (CHRM5, ACM5) GPR21 (GPR21, GPRL) GPR27 (GPR27) GPR45 (GPR45, PSP24) GPR52 (GPR52) GPR61 (GPR61) GPR62 (GPR62) GPR63 (GPR63) GPR78 (GPR78) GPR84 (GPR84) GPR85 (GPR85) GPR88 (GPR88) GPR101 (GPR101) GPR161 (GPR161, RE2) GPR173 (GPR173, SREB3)
Subfamily A19 5-Hydroxytryptamine (5-HT) receptor IPR002231 5-HT1A (HTR1A, 5H1A) 5-HT1B (HTR1B, 5H1B) 5-HT1D (HTR1D, 5H1D) 5-HT1E (HTR1E, 5H1E) 5-HT1F (HTR1F, 5H1F) 5-HT4 (HTR4) IPR001520 5-HT5A (HTR5A, 5H5A) 5-HT7 (HTR7, 5H7) IPR001069
Unclassified Olfactory receptor IPR000725 Vomeronasal receptor IPR004072 VN1R1 VN1R2 VN1R3 VN1R4 VN1R5

Impressum                                     Zuletzt geändert am 17.11.2013 16:12