| zurück Home | brusterhaltende Therapie des Mamma - Karzinoms | ||||||||
| allgemeines | Die brusterhaltende Therapie des Mammakarzinoms besteht aus Operation und Strahlentherapie | Von einer Außenseitermethode hat sie sich inzwischen zur Standardtherapie entwickelt. | |||||||
| Brusterhaltung - Ablatio | |||||||||
| intramammäre Rezidive | |||||||||
| Dosierung | Gesamte Brust: | 50 Gy, ED 2Gy oder | 50,4 Gy, ED 1,8 Gy | verkürzt: 39,9 Gy, ED 2,66Gy | |||||
| Boost | |||||||||
| IMRT | |||||||||
| APBI | Accelerated partial breast irradiation | ASTRO - Guidelines: Kriterien für die Eignung | APBI versus WBI | ||||||
| Brachytherapie | MammoSite | Ballonkatheter | |||||||
| Intrabeam | 50kV-Röntgenstrahlung | Halle: Praxis Heider, Uni Köln, Klinikum Nürnberg, MHH Hannover | |||||||
| bleibende Veränderungen |
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| Quellen |
1.) Kurtz JM, Spitalier JM, Amalric R, et al.: The prognostic significance of late local recurrence after breast-conserving therapy. Int J Radiat Oncol Biol Phys 18(1990):87-93 2.) Arriagada R, Le MG, Guinebretiere JM, Dunant A, Rochard F, Tursz T: Late local recurrences in a randomised trial comparing conservative treatment with total mastectomy in early breast cancer patients. Ann Oncol 14(2003):1617-1622 3.) Huang E, Buchholz TA, Meric F, et al.: Classifying local disease recurrences after breast conservation therapy based on location and histology: new primary tumors have more favorable outcomes than true local disease recurrences. Cancer 95(2002):2059-2067 4.) Smith TE, Lee D, Turner BC, Carter D, Haffty BG: True recurrence vs. new primary ipsilateral breast tumor relapse: an analysis of clinical and pathologic differences and their implications in natural history, prognoses, and therapeutic management. Int J Radiat Oncol Biol Phys 48(2000):1281-1289 5.) Clarke M, Collins R, Darby S, et al.: Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: An overview of the randomised trials. Lancet 366(2005):2087-2106 | ||||||||
Impressum Zuletzt geändert am 30.11.2013 13:01