zurück | Mamma-Ca: biologischer Subtyp | |||||||||||||||||||||||||||||||
allgemeines | Nach Genexpressionsanalysen werden folgende Subtypen unterschieden (1,2): |
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Klinik (3) |
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Prognose (4) | Verlauf mit metastasiertem Mammakarzinom
PFS-1: Progressionsfreies Überleben nach first-line-Therapie PPS-1: Postprogression Überleben nach first-line-Therapie |
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Quellen |
1.) Sorlie T, et al.: Gene expression pattern of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 98(2001):10869-74 2.) Perou CM, et al.: Molecular portraits of human breast tumours. Nature 406(2000):747-752. 3.) Truong PT, et al.: Is Biological Subtype Prognostic of Locoregional Recurrence Risk in Women With pT1-2N0 Breast Cancer Treated With Mastectomy? Int J Radiation Oncol Biol Phys 88(2014): 57-64 4.) Bonotto M, et al.: Measures of outcome in metastatic breast cancer: insights from a real-world scenario. The Oncologist 19(2014):608-615 | |||||||||||||||||||||||||||||||
Impressum .....................................................................................Zuletzt geändert am 24.07.2014 22:08